Current Protocol Documents 

Please click on the links below to access current REMAP-CAP protocol documents. Different hospitals and countries may have submitted different versions of protocol documents than are listed below.

Core Protocol and Pandemic Appendix

REMAP-CAP Core Protocol

Pandemic Appendix to the Core Protocol

Operational characteristics of the Pandemic Appendix to the Core Protocol

Domain-Specific Appendices

Antibiotic Domain Specific Appendix

Macrolide Duration Domain Specific Appendix

Corticosteroid Domain Specific Appendix

Influenza Antiviral Domain Specific Appendix

COVID-19 Antiviral Domain Specific Appendix

COVID-19 Immune Modulation Domain Specific Appendix

COVID-19 Immunoglobulin Domain Specific Appendix

Anticoagulation Domain Specific Appendix

Vitamin C Domain Specific Appendix

Simvastatin Domain Specific Appendix

Mechanical Ventilation Domain Specific Appendix

Antiplatelet Domain Specific Appendix

ACE2 RAS Modulation Domain Specific Appendix

Cysteamine Domain Specific Appendix

Endothelial Domain Specific Appendix

Influenza Immune Modulation Domain Specific Appendix

Region Specific Appendices

Australia and New Zealand Region Specific Appendix

European Region Specific Appendix

Canadian Region Specific Appendix

Saudi Arabia Region Specific Appendix

United States of America Region Specific Appendix

Japanese Region Specific Appendix

Statistical Appendices

Statistical Analysis Appendix

Please note that given the adaptive nature of this trial, protocol documents may change over time. These documents will be updated periodically as new versions are approved by the International Trial Steering Committee and ethical review boards.

The REMAP-COVID Core Protocol utilised in the United States of America is available upon request.